Toward an Understanding of the Pathophysiology of Chronic Laryngitis Chronic laryngitis, characterized by inflammation of the laryngeal tissues, is the most commonly diagnosed organic voice disorder, yet treatments targeting suspected etiologic factors have demonstrated limited efficacy. A major barrier to the development of improved medical therapies for chronic laryngitis is a fundamental gap in knowledge related to the pathophysiology ... Article
Article  |   March 31, 2016
Toward an Understanding of the Pathophysiology of Chronic Laryngitis
Author Notes
  • Disclosure: Financial: Marie Jetté has no relevant financial interests to disclose.
    Disclosure: Financial: Marie Jetté has no relevant financial interests to disclose.×
  • Nonfinancial: Marie Jetté has no relevant nonfinancial interests to disclose.
    Nonfinancial: Marie Jetté has no relevant nonfinancial interests to disclose.×
Article Information
Speech, Voice & Prosodic Disorders / Voice Disorders / Speech, Voice & Prosody / Part 1
Article   |   March 31, 2016
Toward an Understanding of the Pathophysiology of Chronic Laryngitis
Perspectives of the ASHA Special Interest Groups, March 2016, Vol. 1, 14-25. doi:10.1044/persp1.SIG3.14
History: Received September 14, 2015 , Revised October 21, 2015 , Accepted October 27, 2015
Perspectives of the ASHA Special Interest Groups, March 2016, Vol. 1, 14-25. doi:10.1044/persp1.SIG3.14
History: Received September 14, 2015; Revised October 21, 2015; Accepted October 27, 2015

Chronic laryngitis, characterized by inflammation of the laryngeal tissues, is the most commonly diagnosed organic voice disorder, yet treatments targeting suspected etiologic factors have demonstrated limited efficacy. A major barrier to the development of improved medical therapies for chronic laryngitis is a fundamental gap in knowledge related to the pathophysiology of laryngeal inflammation. This article provides a review of the literature specific to laryngeal immunity in health and disease.

Acknowledgements
The author acknowledges funding support from NIH/NIDCD R01-9600 (Dr. Susan Thibeault), T32-9401 (Dr. Diane Bless), and T32-12280 (Dr. Sue Kinnamon).
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